Graves Hyper  thyroidalalism and Associated Conditions    November 15, 2011    Graves disease is an autoimmune  disturb of the  endocrinal organization, specifically affecting the thyroid gland and its  discriminations1.   The  tender-hearted endocrine system is comprised of numerous glands located throughout the body.    separately of the glands that make up the parts of the endocrine system produces  hormones that  atomic number 18 secreted into the blood.   Once in the bloodstream, hormones are  commensurate to travel   ample distances to target  create from raw materials and organs within the body  creating effects that   toilette last as short as a   precisely a(prenominal) minutes, or as long as several months10.    Upon  comer at a targeted organ or tissue, hormones are  subject to affect many things such as: metabolism, chemical balance, and  fruitful function10.     The thyroid gland in humans is located superficially to the sternum, but below the Adams apple in the lower ve   ntral portion of the neck, wrapping around the   verbalise box and trachea10.   The thyroid gland is a butterfly-shaped organ comprised of  both lobes dual-lane by a thin tissue called the isthmus10.   The tissue of the thyroid is made up of specialized cells organized into  world-wide groups called follicular cells.   Pituitary gland secretions referred to as thyroid stimulant hormone ( thyrotrophin) or thyotropin stimulate the follicular cells5.

    thyroid-stimulating hormone secretion is a negative feedback loop in which the  hypophysis gland  meet is dependant upon the level of thyroid hormone in the blood.   If t   hither is too much thyroid hormone in the bl!   ood, the pituitary gland shuts down the  takings of TSH, which in turn, slows the  end product of thyroid hormone until normal hormonal levels are obtained, and production of TSH becomes necessary again9.   In a properly  cognitive operation thyroid,  excite follicular cells  pluck up free TSH from the blood, and  curb to receptors specific for the hormone that reside on the  satellite tissue layer of the follicle.   This bound compound activates an affinity for iodine, and  activate follicular cells pick up free...If you want to get a full essay,  coiffe it on our website: 
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